Revisiting Global Gene Expression Analysis

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Revisiting Global Gene Expression Analysis

Gene expression analysis is a widely used and powerful method for investigating the transcriptional behavior of biological systems, for classifying cell states in disease, and for many other purposes. Recent studies indicate that common assumptions currently embedded in experimental and analytical practices can lead to misinterpretation of global gene expression data. We discuss these assumptio...

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ژورنال

عنوان ژورنال: Cell

سال: 2012

ISSN: 0092-8674

DOI: 10.1016/j.cell.2012.10.012